Microcalorimeters

TA Instruments’ Isothermal Titration Calorimetry (ITC), Differential Scanning Calorimetry (DSC), and Isothermal Calorimetry systems are powerful analytical techniques for in-depth characterization of molecular binding events and structural stability. Thermodynamic binding signatures not only reveal the strength of a binding event, but the specific or nonspecific driving forces involved. Structural stability profiles from DSC reveal strengths and weaknesses in higher order structure and define the behavior of individual domains and their interactions.

Microcalorimeters
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Instrument Categories

Differential Scanning Calorimetry

TA Instruments’ microcalorimeter DSC’s are powerful tools with unmatched sensitivity for the characterization of molecular structure and molecular stability of in-solution or solid/semi-solid samples.

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Differential Scanning Calorimetry

Isothermal Titration Calorimetry

TA Instruments’ Affinity ITC and Nano ITC series calorimeters perform with the highest sensitivity and unmatched flexibility for the characterization of any molecular interaction. With the best baseline stability available on any ultrasensitive ITC instrument, and the easy-to-use experimental design flexibility, the data quality and reproducibility from these instruments will enhance laboratory throughput with the highest quality results.

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Isothermal Titration Calorimetry

Isothermal Microcalorimetry

Isothermal Microcalorimetry is an extremely sensitive technique complementary to TA Instruments differential scanning calorimeters. TAM is a microcalorimeter system represented by TAM IV, TAM IV-48 and TAM Air.

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Isothermal Microcalorimetry

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