Breakthrough BET technology that delivers automation and compliance

The innovative Sievers Eclipse automated endotoxin detection platform decreases assay setup time by up to 85% and reduces Limulus Amebocyte Lysate (LAL) reagent use by up to 90% while meeting all requirements of the harmonized pharmacopeia: USP <85>, EP 2.6.14 and JP 4.01. Through groundbreaking technology, the Eclipse endotoxin testing solution significantly decreases pipetting steps, reduces operator-to-operator variability, and simplifies BET test setup. The Eclipse platform leverages precise microfluidic liquid handling and embedded endotoxin to automate kinetic chromogenic assays. Throughput of 21 samples per plate is maintained without the complexity of robotics or the time and technique demands of a traditional LAL test.

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Eclipse Platform Lab Features & Benefits

  • Enables fully compliant, 21-sample assay setup in as little as 9 minutes
  • Reduces Limulus Amebocyte Lysate (LAL) reagent use by up to 90%
  • Meets all requirements of the harmonized pharmacopoeia: USP <85>, EP 2.6.14 and JP 4.01
  • Embedded endotoxin for a standard curve and PPCs

Features & Benefits

Despite the need for easier, automated, and more sustainable solutions for endotoxin testing, many platforms fall short of meeting key requirements or streamlining installation and validation for easy adoption. With the Sievers Eclipse, you get the benefits of significantly easier BET assay setup and full compliance, without the complexity of robotics or difficult implementation.

The Sievers Eclipse BET Platform and enterprise software provide:

  • 9-minute setup for 21-sample assay (time-savings of up to 85%)
  • Reduction in LAL reagent by up to 90%
  • Compliance with all requirements of the harmonized pharmacopeia: USP <85>, EP 2.6.14 and JP 4.01
  • Highly customizable software with full compliance with 21 CFR Part 11 and ALCOA+
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Learn more about Eclipse Bacterial Endotoxins Testing

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